About our One Health Initiative

The Institute for Healthcare Innovation (IHI) fosters Midwestern University’s One Health initiative and clinical research capabilities for all professional disciplines at Midwestern University. One Health is an initiative that integrates the collaboration of all healthcare professionals including physicians, veterinarians, and environmental scientists. The objective is the improvement of health of all species.

About Translational Medicine

Translational research (translational medicine) involves the collaboration of various disciplines and expertise to advance medical discoveries (disease prevention, diagnosis, and treatment).   The IHI has a collaborative approach to clinical research by bringing together basic research with our various clinical programs in Veterinary Medicine, Osteopathic Medicine, Dental Medicine, Pharmacy and Health Sciences.

Translational medicine’s foundation lies with a better understanding of how a new treatment may translate into a medical benefit. Since many pet diseases are so similar to human diseases, evaluating naturally occurring diseases in pets is one method to understanding how the therapy may benefit people.

Pets share many similar diseases to people

Pets share many similar diseases to people – here are just a few common diseases and conditions affecting people and pets:
cancer (melanoma, mammary carcinoma, osteosarcoma, lymphoma, and soft tissue sarcomas)

  • musculoskeletal(osteoarthritis, tendon and ligament injuries)
  • ophthalmic(dry eye, corneal surface diseases, cataracts)
  • infections(viral, fungal, and bacterial)
  • metabolic (diabetes mellitus, Cushing’s disease, Addison’s disease, and hypothyroidism)
  • cardiovascular(congestive heart failure, dilative cardiomyopathy, hypertrophic cardiomyopathy)
  • pulmonary(asthma, obstructive airway disease)
  • immune mediated(inflammatory bowel disease, autoimmune disorders, atopic dermatitis)

Examples of our Translational Medicine Capabilities

  • Dental Medicine: evaluating inflammatory markers in dogs with periodontal disease as a translational model for human periodontal disease.
  • Cancer: examining solid tumors in dogs to better understand the dynamics of cancer.
  • Infectious Disease: evaluation of systemic cytokines in canine fungal infections to better understand immunological changes during the course of disease.

Our campus is equipped with state of the art research equipment and clinical diagnostic equipment to facilitate research in ophthalmology, orthopedics, dermatology, cardiology, immunology, and other medical disciplines.

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